BLOOMINGTON – Indiana Governor Mike Braun cut the ribbon on Simtra BioPharma Solutions’ latest expansion in Bloomington today, celebrating the company’s more than $250 million investment in its Indiana operations. The expansion will increase the company’s state-of-the-art manufacturing capabilities and strengthen the state’s life sciences sector, which already ranks No. 1 in the U.S. for exports.

“Indiana’s life sciences industry continues to lead with the investment and innovation of companies like Simtra BioPharma Solutions,” said Gov. Braun. “The company’s $250 million expansion that we celebrate today will pave the way for new high-wage jobs and continued, long-term growth here in Bloomington.”


Simtra, a leading contract development and manufacturing organization (CDMO) specializing in sterile injectables, recently completed construction of a purpose-built two-story, 153,000-square-foot facility at its main campus in Bloomington. The facility, known as Building H, houses three isolator commercial-scale sterile filling lines, expanding the company’s manufacturing capabilities with suites for high-speed filling of syringes and vials, each with dedicated formulation/compounding rooms.

Today’s grand opening is the first major milestone of Simtra’s planned growth in Bloomington. Last year, the company acquired a 65-acre property nearby with more than 300,000 square feet of available space for future development. The company, which employs more than 1,600 associates in Indiana, expects the Building H expansion to create hundreds of new, high-wage jobs.

“Building H represents a milestone in Simtra’s growth strategy and our continuing expansion in Bloomington,” said Franco Negron, chief executive officer of Simtra BioPharma Solutions. “We are investing in the capacity, technology and infrastructure our customers need to develop and manufacture increasingly complex injectable medicines. With major investments across our existing sites, we are building a global manufacturing network designed to grow with our customers, support patients and contribute to the communities we operate in.”
Simtra is part of a robust Indiana life sciences sector that ships $36 billion in products, including pharmaceuticals and medical devices, annually, ranking No. 1 in the U.S. The sector contributes $102 billion to the state’s economy.

“Indiana continues to strengthen its reputation as a global destination for developing and producing life-changing and life-saving solutions,” said Indiana Secretary of Commerce Chuck Goodrich. “Simtra’s commitment to growing in Indiana will create more high-wage career opportunities for Hoosiers while ensuring that our state remains at the center of the global life sciences sector.”
Simtra’s investment in Bloomington is part of the company’s global strategy to deliver high-quality sterile manufacturing solutions in therapeutic areas such as oncology medicines. The company produces nearly 200 million sterile units annually across its facilities and currently manufactures six of the 17 approved ADCs globally. Simtra operates facilities in Bloomington, Indiana, and Halle/Westfalen, Germany. With more than 65 years of manufacturing expertise, Simtra combines deep technical know-how and global reach to help pharma and biotech innovators bring complex medicines to patients.
The company’s Building H expansion was supported with $500,000 in READI 2.0 funding as part of the 10-county Indiana Uplands region led by Regional Opportunity Initiatives (ROI). Indiana’s READI program is a $1.25 billion investment in regional-led strategies designed to strengthen communities, retain and attract top talent, and increase opportunities for Hoosiers for years to come.


