(INDIANAPOLIS, IN) - The Indianapolis Colts started off the preseason with a 37-17 loss to the San Francisco 49ers.
Quarterback Peyton Manning had a solid start with 91 yards in 16 plays.
Running back Joseph Addai scored a touchdown during that time.
Backup quarterback Curtis Painter wasn't as successful, throwing for just 64 yards and three interceptions.
The Colts have a short week this week as they head to Toronto to take on the Buffalo Bills on Thursday.
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