(INDIANAPOLIS, IN) - The Colts face the San Francisco 49ers Sunday at Lucas Oil Stadium.
The Horseshoes are 6 and 0 for the fourth time in the last five seasons and are riding a league-best 15-game regular season winning streak.
Last Sunday's 42-6 win over the St. Louis Rams gave the Colts a two and-a-half-game lead over second-place Houston in the AFC south.
The Texans beat the 49ers 24-21 last Sunday in Houston.
The 49ers are 3 and 3 and are a game behind first-place Arizona in the NFC west.
San Francisco has lost its last two games.
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